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PART 1: Will the healthcare system become a victim of its own success? Chapter 1. Medical progress is a success story that comes with consequences; Chapter 2. Non-communicable diseases are overtaxing our healthcare system; Chapter 3. Digitalization will be a key success factor for the healthcare system of the future; PART 2: Digital technologies are changing patients and healthcare systems Chapter 4. Do-it-yourself medicine; Chapter 5. The digital doctor-patient relationship; Chapter 6. Digital therapeutics; Chapter 7. Digital health data and data security; Chapter 8. Value-based Medicine; Chapter 9. Digital drug development; PART 3: The five pillars of the healthcare system of tomorrow Chapter 10. Re-allocation of roles: Patients gain power – and responsibility; Chapter 11. Digital health data & infrastructure:Data donation is the new blood drive; Chapter 12. Precision medicine:The pill just for me; Chapter 13. Focus on results & transparency:Payment on delivery; Chapter 14. Preventive medicine:Prevention is better than cure;