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Introduction Part I. Generalization of the Existing Experience of Decision Making in Modern Business Systems Chapter 1. The Russian Model of Decision Making in Modern Business Systems; Aleksei V. Bogoviz, Rustem T. Yuldashev, Margarita A. Menshikova, Olga V. Titova and Ekaterina S. Lebedeva Chapter 2. Current Tendencies of Transformation of the Russian Practice of Decision Making in Business Systems; Tatyana B. Leybert and Elvira A. Khalikova Chapter 3. Problems of Decision Making in Business Systems by the Example of Modern Russia’s Industry; Viktor P. Kuznetsov, Ekaterina P. Garina, Natalia S. Andryashina and Elena V. Romanovskaya Chapter 4. Barriers on the Path of Making of Optimal Decisions in Business Systems by the Example of Modern Russia; Larisa A. Ilyina, Yuliya A. Panteleeva, Dmitry L. Skipin and Alexandra N. Bystrova Chapter 5. Successful Global Experience of Decision Making in Modern Business Systems; Tatyana Y. Anopchenko and Vladislav I. Ostrovskiy Part II. Technologies of Support for Decision Making in Modern Business Systems Chapter 6. The Role and Functions of Mediator in the Process of Decision Making in Modern Business Systems; Aleksei V. Bogoviz, Svetlana V. Lobova, Yulia V. Ragulina, Alexander N. Alekseev and Karine S. Khachaturyan Chapter 7. Innovational Managerial Technologies of Decision Making in the Sphere of Digital Medicine in Modern Business System; Sergey V. Shkodinsky, Elena A. Kondratyeva, Igor V. Bulava, Igor V. Chistov and Sergey E. Zakutnev Chapter 8. Innovative Management Technologies of Decision-Making in Modern Business Systems; Natalia A. Shchukina and Irina A. Tarasova Chapter 9. Analysis and Support of Decision Making with the Use of Latest Information and Communication Technologies for Development of Social and Economic Area with Regard to Capabilities of Different Categories of Population; M.A. Timoshenko, Aleksey F. Rogachev, L.N. Medvedeva and Kirill E. Tokarev Chapter 10. Intellectual Support for Decisions in Modern Business Systems; Irina V. Gashenko, Elena N. Makarenko, Yuliya S. Zima and Tatyana V. Makarenko Part III. Recommendations for Improving the Process of Decision Making in Modern Business Systems Chapter 11. Perspective Directions of Improving the Process of Decision Making in Business Systems by the Example of Modern Russia; Olga G. Semenyuta, Irina V. Orobinskaya, Neonila M. Shiryaeva and Yuliya A. Kruchanova Chapter 12. The Mechanism of Highly-Effective Decision Making in Modern Business Systems; Larisa A. Ilyina, Vladimir S. Tikhonov, Yuliya S. Sakhno and Natalia V. Viktorova Chapter 13. Strategy of Highly-Efficient Decision Making in Modern Business Systems; Ekaterina S. Kovanova, Angelina E. Kolieva, Raphael F. Mustafin and Zalina B. Tedeeva Chapter 14. The Optimization Model of Decision Making in Modern Business Systems; Irina A. Tarasova, Natalia A. Shchukina, Oksana A. Avdeyuk and Vera V. Nekrasova Chapter 15. Algorithm of Implementation of the Optimization Model of Decision Making in Modern Business Systems; Nataliya V. Asanova, Tatyana E. Kozhanova, Yuliya Y. Andreeva and Vera V. Nekrasova Chapter 16. Development of Tools to Support Decision Making in Evaluating the Performance of State Energy Efficiency Policy (the Case of Russian Regions); Lyudmila Y. Bogachkova , Lidiya S. Guryanova and Shamam G. Khurshudyan Chapter 17. Structuring the Information Base on Production Losses in the Conditions of Effective Production Management; Viktor P. Kuznetsov, Igor E. Mizikovsky, Ekaterina P. Garina, Elena V. Romanovskaya and Nataliya S. Andryashina Conclusions